Αr45 RNA - definition. What is Αr45 RNA
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Αr45 RNA         
  • Figure 1: Covariance Model in stockholm format showing the consensus structure for the αr45 family. Each of the stems represented by the structure line #=GC SS_cons is in a different color. Covariance Model in stockholm format can be downloaded [http://gps-tools2.its.yale.edu/ar45_family.pfam here.]
  • Figure 3: Phylogenetic distribution of known and predicted αr45 [[gene]]s. Gene numbers are based on computational analysis using the program Infernal. Legend: Smr45C = ''Sinorhizobium meliloti'' 1021 (NC_003047), Smedr45C = ''Sinorhizobium medicae'' WSM419 chromosome (NC_009636), Sfr45C = ''Sinorhizobium fredii'' NGR234 chromosome (NC_012587), Atr45C = ''Agrobacterium tumefaciens'' str. C58 chromosome linear (NC_003063), ReCIATr45C = ''Rhizobium etli'' CIAT 652 (NC_010994), Arr45C = ''Agrobacterium radiobacter'' K84 chromosome 1 (NC_011985), Rlt2304r45C = ''Rhizobium leguminosarum'' bv. trifolii WSM2304 (NC_011369), Avr45C = ''Agrobacterium vitis'' S4 chromosome 1 (NC_011989), Rlvr45C = ''Rhizobium leguminosarum'' bv. viciae 3841 (NC_008380), Rlt1325r45C = ''Rhizobium leguminosarum'' bv. trifolii WSM1325 (NC_012850), ReCFNr45C = ''Rhizobium etli'' CFN 42 (NC_007761), Mlr45C = ''Mesorhizobium loti'' MAFF303099 chromosome (NC_002678), Mcr45C = ''Mesorhizobium ciceri'' biovar biserrulae WSM1271 chromosome (NC_014923), Bcr45CII = ''Brucella canis'' ATCC 23365 chromosome II (NC_010104), Bs23445r45CII = ''Brucella suis'' ATCC 23445 chromosome II (NC_010167), Bm16Mr45CII = ''Brucella melitensis'' bv. 1 str. 16M chromosome II (NC_003318), BaS19r45CII = ''Brucella abortus'' S19 chromosome 2 (NC_010740), Bm23457r45CII = ''Brucella melitensis'' ATCC 23457 chromosome II (NC_012442), Bs1330r45CII = ''Brucella suis'' 1330 chromosome II (NC_004311), Ba19941r45CII = ''Brucella abortus'' bv. 1 str. 9-941 chromosome II (NC_006933), Bmar45CII = ''Brucella melitensis'' biovar Abortus 2308 chromosome II (NC_007624), Bor45CII = ''Brucella ovis'' ATCC 25840 chromosome II (NC_009504), Bmir45CII = ''Brucella microti'' CCM 4915 chromosome 2 (NC_013118), Oar45C = ''Brucella anthropi'' ATCC 49188 chromosome 2 (NC_009668), MsBNCr45C = ''Mesorhizobium'' sp. BNC1 (NC_008254), Bahr45C = ''Bartonella henselae'' str. Houston-1 (NC_005956), Bacr45C = ''Bartonella clarridgeiae'' 73 (NC_014932), Batr45C = ''Bartonella tribocorum'' CIP 105476 (NC_010161), Baqr45C = ''Bartonella quintana'' str. Toulouse (NC_005955), Babr45C = ''Bartonella bacilliformis'' KC583 (NC_008783), Bagr45C = ''Bartonella grahamii'' as4aup (NC_012846), Ac571r45C = ''Azorhizobium caulinodans'' ORS 571 (NC_009937), Stnr45C = ''Starkeya novella'' DSM 506 chromosome (NC_014217), Xar45C = ''Xanthobacter autotrophicus'' Py2 chromosome (NC_009720), Mesr45C = ''Methylocella silvestris'' BL2 chromosome (NC_011666), Beir45C = ''Beijerinckia indica'' subsp. indica ATCC 9039 chromosome (NC_010581), Rhpr45C = ''Rhodopseudomonas palustris'' BisA53 chromosome (NC_008435).
  • Figure 4: Alignment of the promoter region of αr45 members. All members presented putative σ<sup>70</sup> promoters with -35 and -10 boxes marked in green and red respectively.
  • Figure 5: Genomic context scheme of Smr45C and its closest homologues in other organisms. The αr45 RNA genes are represented by red arrows and the flanking ORFs by arrows on different colors depending on their product function (legend). Numbers indicate the αr45 RNA gene's and flanking ORFs coordinates in each organism genome database. The gene strand is represented with the file direction. On the left of the figure identification names are used which correspond to a certain organism: αr45_Smr45C = ''Sinorhizobium meliloti'' 1021 (NC_003047), αr45_Smedr45C = ''Sinorhizobium medicae'' WSM419 chromosome (NC_009636), αr45_Sfr45C = ''Sinorhizobium fredii'' NGR234 chromosome (NC_012587), αr45_Atr45C = ''Agrobacterium tumefaciens'' str. C58 chromosome linear (NC_003063), αr45_ReCIATr45C = ''Rhizobium etli'' CIAT 652 (NC_010994), αr45_Arr45C = ''Agrobacterium radiobacter'' K84 chromosome 1 (NC_011985), αr45_Rlt2304r45C = ''Rhizobium leguminosarum'' bv. trifolii WSM2304 (NC_011369), αr45_Avr45C = ''Agrobacterium vitis'' S4 chromosome 1 (NC_011989), αr45_Rlvr45C = ''Rhizobium leguminosarum'' bv. viciae 3841 (NC_008380), αr45_Rlt1325r45C = ''Rhizobium leguminosarum'' bv. trifolii WSM1325 (NC_012850), αr45_ReCFNr45C = ''Rhizobium etli'' CFN 42 (NC_007761), αr45_Mlr45C = ''Mesorhizobium loti'' MAFF303099 chromosome (NC_002678), αr45_Mcr45C = ''Mesorhizobium ciceri'' biovar biserrulae WSM1271 chromosome (NC_014923), αr45_Bcr45CII = ''Brucella canis'' ATCC 23365 chromosome II (NC_010104), αr45_Bs23445r45CII = ''Brucella suis'' ATCC 23445 chromosome II (NC_010167), αr45_Bm16Mr45CII = ''Brucella melitensis'' bv. 1 str. 16M chromosome II (NC_003318), αr45_BaS19r45CII = ''Brucella abortus'' S19 chromosome 2 (NC_010740), αr45_Bm23457r45CII = ''Brucella melitensis'' ATCC 23457 chromosome II (NC_012442), αr45_Bs1330r45CII = ''Brucella suis'' 1330 chromosome II (NC_004311), αr45_Ba19941r45CII = ''Brucella abortus'' bv. 1 str. 9-941 chromosome II (NC_006933), αr45_Bmar45CII = ''Brucella melitensis'' biovar Abortus 2308 chromosome II (NC_007624), αr45_Bor45CII = ''Brucella ovis'' ATCC 25840 chromosome II (NC_009504), αr45_Bmir45CII = ''Brucella microti'' CCM 4915 chromosome 2 (NC_013118), αr45_Oar45C = ''Brucella anthropi'' ATCC 49188 chromosome 2 (NC_009668), αr45_MsBNCr45C = ''Mesorhizobium'' sp. BNC1 (NC_008254), αr45_Bahr45C = ''Bartonella henselae'' str. Houston-1 (NC_005956), αr45_Bacr45C = ''Bartonella clarridgeiae'' 73 (NC_014932), αr45_Batr45C = ''Bartonella tribocorum'' CIP 105476 (NC_010161), αr45_Baqr45C = ''Bartonella quintana'' str. Toulouse (NC_005955), αr45_Babr45C = ''Bartonella bacilliformis'' KC583 (NC_008783), αr45_Bagr45C = ''Bartonella grahamii'' as4aup (NC_012846), αr45_Ac571r45C = ''Azorhizobium caulinodans'' ORS 571 (NC_009937), αr45_Stnr45C = ''Starkeya novella'' DSM 506 chromosome (NC_014217), αr45_Xar45C = ''Xanthobacter autotrophicus'' Py2 chromosome (NC_009720), αr45_Mesr45C = ''Methylocella silvestris'' BL2 chromosome (NC_011666), αr45_Beir45C = ''Beijerinckia indica'' subsp. indica ATCC 9039 chromosome (NC_010581), αr45_Rhpr45C = ''Rhodopseudomonas palustris'' BisA53 chromosome (NC_008435).
αr45 is a family of bacterial small non-coding RNAs with representatives in a broad group of α-proteobacteria from the order Hyphomicrobiales. The first member of this family (Smr45C) was found in a Sinorhizobium meliloti 1021 locus located in the chromosome (C).
Antisense RNA         
RNA MOLECULES HYBRIDIZING TO COMPLEMENTARY SEQUENCES IN EITHER RNA OR DAN, ALTERING THE FUNCTION OF THE LATTER
Rna, antisense; Antisense rna; Antisense mRNA; Anti-sense RNA; AsRNA; Antisense gene
Antisense RNA (asRNA), also referred to as antisense transcript, natural antisense transcript (NAT) or antisense oligonucleotide, is a single stranded RNA that is complementary to a protein coding messenger RNA (mRNA) with which it hybridizes, and thereby blocks its translation into protein. asRNAs (which occur naturally) have been found in both prokaryotes and eukaryotes, and can be classified into short (200 nucleotides) non-coding RNAs (ncRNAs).
RNA editing         
  • The effect of C-to-U RNA editing on the human ApoB gene
  • The Editosome Complex
  • Summary of the Various Functions of RNA Editing
COVALENT ALTERATION OF ONE OR MORE NUCLEOTIDES WITHIN AN RNA MOLECULE TO PRODUCE AN RNA MOLECULE WITH A SEQUENCE THAT DIFFERS FROM THAT CODED GENETICALLY
RNA Editing; Rna editing; Editosome; RNA modification
RNA editing (also RNA modification) is a molecular process through which some cells can make discrete changes to specific nucleotide sequences within an RNA molecule after it has been generated by RNA polymerase. It occurs in all living organisms and is one of the most evolutionarily conserved properties of RNAs.